Saturday, December 17, 2011

Mercury, mercury, where art thou mercury?

I can't even count how many times people have said to me, "Where would your children get mercury poisoning??"  Most people don't realize they encounter this nasty heavy metal every day.  You don't need to have silver fillings to be toxic, although, if you do, it's likely you ARE toxic.

The reason we are accumulating these toxins is, because of an inability to detox naturally.  There are many systems associated with our ability to detox, from the liver to hormones and even nutritional status.  Our bodies are like fine-tuned engines, we require a specific form of "fuel" to function optimally.  When any of these pieces are out of place, the strain on the body is great.  If we can't detox, not only do the toxins pile up causing increased symptoms, but the ability to detox is continuously reduced in the process.  The snow ball just keeps growing and growing.

So where can we find mercury?

-High efficiency light bulbs - supposedly "green".....green my ass!  Imagine what  would happen, if everyone is MANDATED to use these and they end up in landfills daily.  What then?  You think the autism rates are high now, just wait!  Mark my words.  Thank goodness, that has currently been overturned.  Break one of these suckers and you have just reproduced a mini hazardous waste site in your home.  And did you know there is actually a procedure on how to handle it?  I bet you never looked that up, just in case your battery breaks.  No one plans on breaking a bulb, that is why it is called an accident!  Here are the EPA's guidelines, notice they downplay the situation a bit, but still bring attention to the fact that there IS a way to do it, as well as a way NOT to do it!  Hello, safety issue?!

-Lighting and Electrical Applications - Fluorescent lamps are commonly found in garages and home workshop areas, they buzz and crackle when you turn them on, lol.  Spent lamps must be managed properly, because they contain mercury.  A number of communities have begun to collect lamps from residents (not mine) and from their municipal buildings. Careful handling and storage is essential so that mercury is not released via breakage.  If you do break one, refer to the link above for the EPA clean-up guidelines.

-Batteries - The best thing I can do for this topic is provide this link which goes into great detail about the types of mercury in batteries (with specifics) and which companies are phasing mercury out of their batteries.  There aren't enough companies on that list, as far as I am concerned!  The issue here isn't just related to exposure to the batteries themselves, but the production of them.  How many families are effected by the factory jobs related to making them?  What is this mercury doing to our environment?  It doesn't take a rocket scientist to figure it out.

-Fish/seafood - There used to be fish that were deemed safe, now there are fish that are "safer"....get that distinction?  They used to say that you should just avoid the big fish, like Tuna, but now, eat too much fish, period, and you will have a mercury problem, guaranteed.  Just ask Jeremy Pivens who was eating a lot of Sushi (high grade fish) and became toxic enough that he required chelation therapy!  See his story here.

Good news to my ears is that Maine lobsters remain to be the lowest in mercury, yippee for our trips to Maine every year.  That is one luxury I am not yet willing to give up for myself or our kids.  It's a tradition and it's YUMMY....heck, it's only once a year and it's a perfect match for our ghee (clarified butter, which is normally used in restaurants for lobster and is also casein-free)!

-Vaccines - ok, so this requires it's own book completely, which is why there are many out there, but what I would like to say on this topic is that independent studies have confirmed that there are still vaccinations made with mercury and even though they are not necessarily listed on the ingredients like they are with the more obvious flu and Hep B vaccines.  In order for mercury to make it to a label, there has to be over a certain amount.  When mercury is used in the production of a vaccination (and most are) they remove it afterwards, leaving traces behind, low enough that they don't required label identification.  This was taken directly from the FDA website:

FDA is continuing its efforts toward reducing or removing thimerosal from all existing vaccines. Much progress has been made to date. FDA has been actively working with manufacturers, particularly those that manufacture childhood vaccines, to reach the goal of eliminating thimerosal from vaccines, and has been collaborating with other PHS agencies to further evaluate the potential health effects of thimerosal. In this regard, all vaccines routinely recommended for children 6 years of age or younger and marketed in the U.S. contain no thimerosal or only trace amounts (1 microgram or less mercury per dose), with the exception of inactivated influenza vaccine, which was first recommended by the Advisory Committee on Immunization Practices in 2004 for routine use in children 6 to 23 months of age.

Then they go and add a nice dose of aluminum to that very vaccine, now you have a recipe for disaster, literally.  Are you worried yet?  If not, you should be!  Mixing aluminum and mercury is a biohazard occurring right in your body (or the body of your innocent and very small child, or both, if you are pregnant).  Mercury levels above 58 micrograms (mcg), millionths of a gram, are associated with neurodevelopmental effects in the fetus, the CDC report states.  Did you know that flu shots still contain 24-25mcg/.5mL?  This is reported by the Institute for Vaccine Safety.  What I find interesting is that you will never find both of these pieces of information on either of their sites, together.  Gee, I wonder why.

Again, taken right from the FDA

As a vaccine preservative, thimerosal is used in concentrations of 0.003% to 0.01%. A vaccine containing 0.01% thimerosal as a preservative contains 50 micrograms of thimerosal per 0.5 ml dose or approximately 25 micrograms of mercury per 0.5 mL dose. The use of mercury-containing preservatives in vaccines has declined markedly since 1999.

DECLINED....not removed entirely. 

-Amalgam fillings - My favorite mercury topic, by far.....50% mercury, by weight.  Did your dentist tell you that before he filled all those pretty white teeth with the only insurance-approved metal?  Probably not, in fact, even when asked now, many dentists won't even acknowledge the question, or they shrug it off with a callused, "it isn't enough to harm you".  Oh, and one I really like, "It's the same as eating a can of tuna fish".  Yeah, maybe if it was organic and that doesn't even matter, because both are dangerous to your health, so what do you think is happening as each one of your fillings off-gas mercury vapors day in and day out, maybe more like eating a can of tuna fish every hour!!   Check out "Smoking Teeth" from the International Academy of Oral Medicine and Toxicology and learn exactly how much mercury is releasing from just one filling all day, then multiply that by the number of fillings you are lucky enough to have.  Serious exposure there!  Mercury DOES cross the placenta and travel through breast milk then to add insult to injury, we pass down three generations of heavy metals adding each of our own toxicities to the mix, get the picture yet?  THEN, take a look at the symptoms of mercury toxicity and put them beside the symptoms of autism, better yet, just get out a mirror, because, surprise, surprise - they are the same.  The cascade of health deterioration with mercury involved is very real and it makes other illnesses much more severe, such as parasitic infections, Lyme Disease, and mold toxicity.  I bet if any Lyme patient was looked at a bit more closely, you would find mercury toxicity.   For many of these autoimmune diseases, they are just the tip of the iceberg....
                                                            MERCURY POISONING                        AUTISM


Psychiatric Social deficits, shyness, social withdrawal Social deficits, social withdrawal, shyness
Disturbances Depression, mood swings; mask face Depressive traits, mood swings; flat affect
  Anxiety Anxiety
  Schizoid tendencies, OCD traits Schizophrenic & OCD traits; repetitiveness
  Lacks eye contact, hesitant to engage others Lack of eye contact, avoids conversation
  Irrational fears Irrational fears
  Irritability, aggression, temper tantrums Irritability, aggression, temper tantrums
  Impaired face recognition Impaired face recognition
     
Speech, Loss of speech, failure to develop speech Delayed language, failure to develop speech
Language & Dysarthria; articulation problems Dysarthria; articulation problems
Hearing Speech comprehension deficits Speech comprehension deficits
Deficits Verbalizing & word retrieval problems Echolalia; word use & pragmatic errors
  Sound sensitivity Sound sensitivity
  Hearing loss; deafness in very high doses Mild to profound hearing loss
  Poor performance on language IQ tests Poor performance on verbal IQ tests
     
Sensory Abnormal sensation in mouth & extremities Abnormal sensation in mouth & extremities
Abnormalities Sound sensitivity Sound sensitivity
  Abnormal touch sensations; touch aversion Abnormal touch sensations; touch aversion
  Vestibular abnormalities Vestibular abnormalities
     
Motor Disorders Involuntary jerking movements - arm flapping, ankle jerks, myoclonal jerks, choreiform movements, circling, rocking Stereotyped movements - arm flapping, jumping, circling, spinning, rocking; myoclonal jerks; choreiform movements
  Deficits in eye-hand coordination; limb apraxia; intention tremors Poor eye-hand coordination; limb apraxia; problems with intentional movements
  Gait impairment; ataxia – from incoordination & clumsiness to inability to walk, stand, or sit; loss of motor control Abnormal gait and posture, clumsiness and incoordination; difficulties sitting, lying, crawling, and walking
  Difficulty in chewing or swallowing Difficulty chewing or swallowing
  Unusual postures Unusual postures
     
Cognitive Impairments Borderline intelligence, mental retardation - some cases reversible Borderline intelligence, mental retardation - sometimes "recovered"
  Poor concentration, attention, response inhibition Poor concentration, attention, shifting attention
  Uneven performance on IQ subtests Uneven performance on IQ subtests
  Verbal IQ higher than performance IQ Verbal IQ higher than performance IQ
  Poor short term, verbal, & auditory memory Poor short term, auditory & verbal memory
  Poor visual and perceptual motor skills, impairment in simple reaction time Poor visual and perceptual motor skills, lower performance on timed tests
  Difficulty carrying out complex commands Difficulty carrying out multiple commands
  Alexia (inability to comprehend the meaning of written words) Hyperlexia (ability to decode words while lacking word comprehension)
  Deficits in understanding abstract ideas & symbolism; degeneration of higher mental powers Deficits in abstract thinking & symbolism, understanding other’s mental states, sequencing, planning & organizing
(ii)

Unusual
Stereotyped sniffing (rats) Stereotyped, repetitive behaviors
Behaviors ADHD traits ADHD traits
  Agitation, unprovoked crying, grimacing, staring spells Agitation, unprovoked crying, grimacing, staring spells
  Sleep difficulties Sleep difficulties
  Eating disorders, feeding problems Eating disorders, feeding problems
  Self injurious behavior, e.g. head banging Self injurious behavior, e.g. head banging
     
Visual Poor eye contact, impaired visual fixation Poor eye contact, problems in joint attention
Impairments “Visual impairments,” blindness, near-sightedness, decreased visual acuity “Visual impairments”; inaccurate/slow saccades; decreased rod functioning
  Light sensitivity, photophobia Over-sensitivity to light
  Blurred or hazy vision Blurred vision
  Constricted visual fields Not described
     
Physical Disturbances Increase in cerebral palsy; hyper- or hypo-tonia; abnormal reflexes; decreased muscle strength, especially upper body; incontinence; problems chewing, swallowing, salivating Increase in cerebral palsy; hyper- or hypotonia; decreased muscle strength, especially upper body; incontinence; problems chewing and swallowing
  Rashes, dermatitis/dry skin, itching; burning Rashes, dermatitis, eczema, itching
  Autonomic disturbance:  excessive sweating, poor circulation, elevated heart rate Autonomic disturbance:  unusual sweating, poor circulation, elevated heart rate
     
Gastro-intestinal Gastroenteritis, diarrhea; abdominal pain, constipation, “colitis” Diarrhea, constipation, gaseousness, abdominal discomfort, colitis
Disturbances Anorexia, weight loss, nausea, poor appetite Anorexia; feeding problems/vomiting
  Lesions of ileum & colon; increases gut permeability Leaky gut syndrome
  Inhibits dipeptidyl peptidase IV, which cleaves casomorphin Inadequate endopeptidase enzymes needed for breakdown of casein & gluten
     
Abnormal Biochemistry Ties up -SH groups; blocks sulfate transporter in intestines, kidneys Low sulfate levels
  Has special affinity for purines & pyrimidines Purine & pyrimidine metabolism errors lead to autistic features
  Reduces availability of glutathione, needed in cells & liver to detoxify heavy metals Low levels of glutathione; decreased ability of liver to detoxify heavy metals
  Causes significant reduction in  glutathione peroxidase and glutathione reductase Abnormal glutathione peroxidase activities in erythrocytes
  Disrupts mitochondrial activities, especially in brain Mitochondrial dysfunction, especially in brain
     
Immune Dysfunction Sensitivity due to allergic or autoimmune reactions; sensitive individuals more likely to have allergies, asthma, autoimmune-like symptoms, especially rheumatoid-like ones More likely to have allergies and asthma; familial presence of autoimmune diseases, especially rheumatoid arthritis; IgA deficiencies
  Can produce an immune response in CNS On-going immune response in CNS
  Causes brain/MBP autoantibodies  Brain/MBP autoantibodies present
  Causes overproduction of Th2 subset; kills/inhibits lymphocytes, T-cells, and monocytes; decreases NK T-cell activity; induces or suppresses IFNg & IL-2 Skewed immune-cell subset in the Th2 direction; decreased responses to T-cell mitogens; reduced NK T-cell function; increased IFNg & IL-12
CNS Structural Pathology Selectively targets brain areas unable to detoxify or reduce Hg-induced oxidative stress Specific areas of brain pathology; many functions spared
  Damage to Purkinje and granular cells Damage to Purkinje and granular cells
  Accummulates in amygdala and hippocampus Pathology in amygdala and hippocampus
  Causes abnormal neuronal cytoarchitecture; disrupts neuronal migration & cell division; reduces NCAMs Neuronal disorganization; increased neuronal cell replication, increased glial cells; depressed expression of NCAMs
  Progressive microcephaly Progressive microcephaly and macrocephaly
  Brain stem defects in some cases Brain stem defects in some cases
     
Abnormalities in Neuro-chemistry Prevents presynaptic serotonin release & inhibits serotonin transport; causes calcium disruptions Decreased serotonin synthesis in children;  abnormal calcium metabolism
  Alters dopamine systems; peroxidine deficiency in rats resembles mercurialism in humans Possibly high or low dopamine levels; positive response to peroxidine (lowers dopamine levels)
  Elevates epinephrine & norepinephrine levels by blocking enzyme that degrades epinephrine Elevated norepinephrine and epinephrine
  Elevates glutamate Elevated glutamate and aspartate
  Leads to cortical acetylcholine deficiency; increases muscarinic receptor density in hippocampus & cerebellum Cortical acetylcholine deficiency; reduced muscarinic receptor binding in hippocampus
  Causes demyelating neuropathy Demyelation in brain
     
EEG Abnormalities/ Causes abnormal EEGs, epileptiform activity Abnormal EEGs, epileptiform activity
Epilepsy Causes seizures, convulsions Seizures; epilepsy
  Causes subtle, low amplitude seizure activity Subtle, low amplitude seizure activities
     
Population Effects more males than females Male:female ratio estimated at 4:1
Characteristics At low doses, only affects those genetically susceptible High heritability - concordance for MZ twins is 90%
  First added to childhood vaccines in 1930s First "discovered" among children born in 1930s
  Exposure levels steadily increased since 1930s with rate of vaccination, number of vaccines Prevalence of autism has steadily increased from 1 in 2000 (1940s) to 1 in 500 (1990s)
   Exposure occurs at 0 - 15 months; clinical silent stage means symptom emergence delayed; symptoms emerge gradually, starting with movement & sensation Symptoms emerge from 4 months to 2 years old; symptoms emerge gradually, starting with movement & sensation

If that doesn't convince you, I honestly don't know what will.  Thanks to ARC research for this comprehensive list!

-Pesticides - Organochlorine pesticides like Aldrin and Endrin and Dieldrin, used in the United States for decades, were mostly eliminated from use in the late 1980s according to Dr. Gerberding.  So this should make us feel better about pesticides, right?  Well, what about this little tidbit of information?

Mercury is only removed from the biosphere when it reaches sediments deep under the oceans or when it is immobilized in controlled landfills. This implies that, even as we gradually eliminate mercury releases from human activity, levels in the environment will take several decades or longer to go back down.

-Pharmaceuticals - Mercury can be found in some topical disinfectants, like Mercurochrome, Tincture of Merthiolate and older medications for psoriasis and eczema. It is also found in some over-the-counter nasal sprays (yum), hemorrhoidal ointments (child birth anyone?) and eye and contact lens products (ouch).  Be sure to read labels!

-Major appliances - Mercury-containing thermostat probes can be found in several types of gas-fired appliances that have pilot lights, including ranges, ovens, clothes dryers, water heaters, furnaces and space heaters. That little metal probe you've probably noticed in the back of your oven consists of a metal bulb and thin tube attached to a gas-control valve. Also known as a flame sensor or gas safety valve, it prevents gas flow if the pilot light is not lit. Although non-mercury thermostat probes are also used in these appliances, treat all probes as though they contain mercury, unless you know that they do not. If you decide to trash your stove, the probe should be removed and stored in a covered container until it can be taken to a consolidation site.

-Thermometers (fever, candy, deep fry, oven, indoor and outdoor with a silvery temperature indicator) - Thermometers are one of the largest sources of mercury discarded in municipal solid waste. Many communities, including Boston, are now banning the sale of mercury fever thermometers and offering exchanges by giving out mercury-free alternatives such as digital thermometers.  Health Care Without Harm has produced a resource guide entitled “How to Plan and Hold a Mercury Thermometer Exchange.” To obtain a copy, go to Health Care Without Harm.

Important - If you break a thermometer, do not vacuum the mercury up, this will spread it throughout the house. Instead, put on rubber or disposable gloves (not leather work gloves!) and scoop up the silvery liquid with an appropriate utensil. Handle the liquid very carefully and capture it in a firm container with a tight cover. This container should not be reused. Contact your local board of health for additional suggestions on collection and disposal. The collected mercury should be recycled whenever possible.

-Barometers and Manometer - Many barometers and vacuum gauges found in machinery contain mercury. Liquid mercury in the gauges responds to air pressure in a precise way that can be read on a calibrated scale.  Mercury-free alternatives are available.

-Thermostats - Mercury-containing tilt switches have been used in thermostats for more than 40 years. Each switch contains approximately 3 grams of mercury. Electronic thermostats provide many enhanced features and are mercury-free. The manufacturers of thermostats have established a take back program. For information contact the Thermostat Recycling Corporation at 1-800-238-8192.

-Coal and cement plants nearby? - They pollute the air, what more do you need to know?  In all seriousness, mercury exists naturally in coal, making coal-fired power plants the largest source of mercury pollution in this country. Coal accounts for nearly 50% of the electricity generated in this country—and almost 50 tons of mercury emissions annually. According to the nonprofit law firm Earthjustice, all the cement kilns in the U.S. combined pump out roughly 23,000 pounds of mercury every year. The mercury comes from coal, which is used to fuel the cement-manufacturing process, as well as limestone, another natural source of the heavy metal. The group released a report last July finding that, individually, some cement kilns emit nearly one and a half times more mercury than the most polluting coal-fired power plants. But because there are fewer kilns, they account for lower levels of atmospheric mercury overall than coal plants.

-Fossil fuel, and to a lesser extent, gas and oil - I bet you didn't even realize that even electricity releases mercury?!  The EPA reported that U.S. electric utilities released 48 tons of mercury in 1999, the latest year data is available.  More from the EPA:

Mercury is a trace component of all fossil fuels, including natural gas, gas condensates, crude oil, coal, tar sands, and other bitumens. The use of fossil hydrocarbons as fuels provides the main opportunity for releasing emissions of the mercury they contain into the atmospheric environment, but other avenues also exist in production, transportation, and processing systems. These other avenues may provide mercury directly to air, water, or solid waste streams.

-Chlor-alkali plants - Per Rodale, Chlorine bleach, laundry detergent, cheap vinyl purses, shoes, and toys made with polyvinyl chloride (or PVC)—making all these products required the use of chlorine gas at some point. The chlor-alkali plants that produce it use mercury to convert salt to chlorine gas, and to convert salt to caustic soda, or lye, which is then used in products like detergent, plastics, and bleach. The nonprofit Natural Resources Defense Council (NRDC) says that while most modern chlor-alkali plants have switched to mercury-free technology, there are still seven plants in the U.S. that use it, and each one has roughly 200 tons of mercury on site at any given time. An unknown amount of that mercury gets lost during manufacturing, whether to the air or surrounding waterways; a 2006 report from NRDC found that operators at four of these plants could account for only 29 of the 159 tons of the mercury they used from 2000 to 2004. (As Rodale.com reported earlier this year, some of those plants also make the ubiquitous food ingredient high-fructose corn syrup, and may be tainting food products with mercury.) Avoid chlorine-containing products like chlorine bleach, as well as anything made from polyvinyl chloride, including cheap handbags and shower curtains. Also look for chlorine-free paper products; paper production is the sixth largest mercury emitter in this country. Buy unbleached paper towels, coffee filters, and office paper. For the latter, look for the “Totally Chlorine Free” or “Processed Chlorine Free” labels on the package.

If you want to know how all of the plastics in your car measure up in toxicity, check this out!

-High fructose corn syrup (HFCS) which effects condiments like ketchup and BBQ sauces, it's in baby foods and pretty much any sweetened non-organic, pre-packaged food, unless otherwise advertised.  Heinz has actually just created a HFCS-free ketchup, yeay Heinz!  Still not organic, but it's a step in the right direction.

-Trash incinerators - Hazardous waste, medical waste, and regular garbage incinerators release 13.1 tons (or about 26,000 pounds) of mercury every year, according to statistics from the EPA. The mercury comes from all of the common household items listed above, such as compact fluorescent light bulbs and thermostats, and from automobile scrap.

And remember, it's is not just mercury we have to worry about, there are other dangerous metals out there like aluminum in vaccines, arsenic in the air we breath, cadmium and lead in toys, cars, many plastics and the topic of GMOs requires it's own blog entry.

Please note that this list is not even all-inclusive.

Tuesday, December 13, 2011

Bringing biofilm back

We've used the biofilm protocol in the past with Grayson.  It was the only thing that pulled us out of the trenches when his OCD, anger/aggression and tics were out of control.  We had tried antibiotics twice, long courses pulsed, for his Clostridia, e.coli and strep, to no avail.  It never failed, his symptoms always returned within 6-8 weeks.  Biofilm to the rescue!!  No more antibiotics for this household! His last stool test was clean as a whistle!  Only good bacteria to show for, yeah baby!!

Grayson is currently in managed recovery with no more of the above symptoms.  They are GONE!  We know we still have a long healing path ahead of us, because he can't sustain without the supplements and antimicrobials, and he regresses slightly when he is sick or maybe he's just like the rest of us when we are sick, impatient, cranky and tired.  A child doesn't have the filter to control what they think so it comes across as lack of control when it may just be normal sickness response, FINALLY!!  There was a time when he never got sick, hypo-immunity)

I bet you are wondering why we would need to bring the biofilm protocol back then.  Well, it's not for Grayson, it's actually for Gavin!  He has been catching cold after cold since before Thanksgiving.  When he is sick, he is completely unbearable to manage.  He has never been a sensory kid like Grayson, but when he's sick, his clothes bother him, sleeves and socks, his coat bothers his sleeves (figure that one out) and even food textures become an issue suddenly.  His mood is volatile constantly, he looses speech only screaming and yelling for communication.  He is irritated 24/7!!  He has had bloating and the red anal ring the entire time he's been sick as well.  I tried increasing his antimicrobials with no success.

Then it dawned on me....BIOFILM!  If it worked so well with Grayson, it should also work with Gavin now.  I only started it a few days ago and the results are astounding!!  It's bringing back so many memories from using it with Grayson, but it's working SO much faster!  He immediately began having army green BMs which is always a sign of bacteria die off, yippee!!  A few of them even had mucus with them, which we never see.  The red anal ring is gone, just like that!

It's like we flipped a switch on in his brain!  He is speaking in full, thorough sentences, including following through with conversations.  He listens, responds (even uses "yes" instead of "yeah" or "I did" or "I didn't" instead of just "yes" or "no") and carries through to the end of the conversation calmly and appropriately!!  He is using manners on his own, he is cleaning up messes without being forced, he even played in his room alone for over an hour this morning, reading books and playing with trains.  His belly is down, he's patient and cooperative, and best of all, he is HAPPY again!!  Nothing makes me happier!

Today he did puzzles of the Unite States, puzzles he has never even seen before, very hard puzzles with a lot of small pieces.  At first glance, he immediately noticed that a piece of the puzzle (a state) was MISSING from the pieces laid out in front of him.  He pointed to the puzzle board and said, "This one isn't here".  Unbelievable!!  He is absolutely amazing me right now.  To go from the things we were seeing just days ago, to this, it's clear that the biofilm protocol (with the addition of Lauricidin to his natural antimicrobials) is solely responsible, because nothing else has changed and he is even still sick with congestion and a runny nose.

There are times when we need to go back to basics and for us, that means reinstating protocols we have used successfully, in the past.  Since we have used this with Gavin in the past, as well (when he was MUCH younger) I expect it will work it's magic faster this time around, with lasting results hopefully.  All I know is that I will take what I can get, the vacation from the screaming alone is enough to keep me smiling, today anyway.  =)

Saturday, December 10, 2011

Camel milk in the spotlight

This is an informative and entertaining video from TEDx NHH with Sebastian Lindstrom who works with The What Took You So Long Foundation.  He shares bits and pieces of their movie (you will even see Grayson and our Facebook page mentioned), while narrating the experiences of their journey through dozens of countries filming about camel milk.  This is a world wide initiative that is taking place.  We are blessed to be gaining from this momentum. 

Sunday, December 4, 2011

Pharmaceutical minefield

Be careful what you wish for.

We want doctors to listen, we crave guidance from the very souls who inject our children with poison and send them reeling in toxic blood baths.  Why the bittersweet battle?  In one word - MONEY!  We want our children to benefit from our costly health insurance and rightfully so!!  Who wouldn't want their health issues addressed by their doctors and covered by their insurance?!

Be careful what you wish for.

What happens when mainstream doctors finally DO acknowledge that our children are walking medical books rather than genetically neurological head cases?  Are we really ready for that?

Cha-ching!

This is already in the process of happening, so we KNOW what will transpire the minute doctors realize they can cash in on "curing" autism symptoms.  Notice I said curing symptoms?  Mainstream medicine is a pharmaceutical conundrum, the proverbial symptom band-aid, if you will.

Take PANDAS for example.  PANDAS stands for Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcus.   Let's thank ADHD.com for this detailed description of the 5 diagnostic criteria for the diagnosis of PANDAS below.

What are the diagnostic criteria for PANDAS?
Pandas is diagnosed if there is an episodic history of the following symptoms associated with strep infections.

  • Presence of Obsessive-compulsive disorder and/or a tic disorder, ADHD symptoms or oppositional behaviors
  • Association with neurological abnormalities (motor hyperactivity, or adventitious movements, such as choreiform movements)
  • Pediatric onset of symptoms (age 3 years to puberty)
    Episodic course of symptom severity. (symptoms come and go)
  • Association with group A Beta-hemolytic streptococcal infection (GABHS)
  • GABHS evidenced by either a positive throat culture for strep or positive for streptococcus serology (ASOT or AntiDNAse-B)
  • A history of Scarlet Fever or Rheumatic fever
What is an episodic course of symptoms?
Children with PANDAS seem to have dramatic ups and downs in their OCD and/or tic severity. Tics or OCD which are almost always present at a relatively consistent level do not represent an episodic course. Many children with OCD or tics have good days and bad days, or even good weeks and bad weeks. However, patients with PANDAS have a very sudden onset or worsening of their symptoms, followed by a slow, gradual improvement. If they get another strep. infection, their symptoms suddenly worsen again. The increased symptom severity usually persists for at least several weeks, but may last for several months or longer. The tics or OCD then seem to gradually fade away, and the children often enjoy a few weeks or several months without problems. When they have another strep. throat infection the tics or OCD or associated behaviors return just as suddenly and dramatically as they did previously.

It is quickly gaining popularity with mainstream doctors.  And what is their treatment for it, you ask?  Well, medication, of course....pharmaceuticals.  One of the worst things you can do to a child with an autoimmune disorder such as autism is prescribe them antibiotics, it messes with their already dysfunctional immune system.  It tears down the already lacking terrain of their gut and it messes with their ability to fight off ANYTHING, let alone the nasty strep infections.  In fact, one of the reasons people have problems with oxalates, is because antibiotics kill the oxalobacter formigenes bacteria and there is no known way to replenish it, via probiotics.

And when parents become desperate, because antibiotics no longer work (the bacteria become resistant to antibiotics and they build a matrix of biofilm to protect themselves) they are instructed that the only next step for them is a treatment called IVIG where blood plasma with protective antibodies is provided via a blood transfusion.  Sounds ideal, doesn't it....a quick fix?!  One IVIG treatment requires upwards of 10,000 donors!!  Knowing what I know about illnesses like Lyme Disease, you couldn't pay ME to have this done with my kids.  I don't want someone else's undiagnosed illness.  Think about how hard it is to detect Lyme Disease, and how common it's become!! Even, if I were assured and RE-assured that the blood was specifically tested for Lyme Disease (among other illnesses), that would not be enough for me to risk my already fragile kids lives with the possibility that even one of those 10,000 donors could have Lyme Disease.  There are other ways... 

How should PANDAS be treated?  I'm no doctor, of course.  All I can tell you is that our older son had all of the symptoms associated with PANDAS at one point, errrr ok many points...HAD is the key word there though.  I'm not convinced that all of the children being diagnosed with PANDAS actually have it, because many bad bacteria can exhibit the same symptoms.  In fact, although Grayson had Hemolytic Strep bacteria, his more dysbiotic bacteria was Clostridia.  My guess is that none of these doctors are checking their patients for heavy metal toxicity (properly) and I am sure they aren't considering a GFCFSF diet or any other diet for that matter.  Like Lyme, Clostridia, Klebsiella, yeast overgrowth (and so many other pathogenic illnesses), PANDAS responds well to all the same methods of recovery being used in biomedicine. Ironically, camel milk has been compared to doing IVIG, perhaps this is one of the other reasons we are seeing such results with our treatment choices.  If you want to learn more about why camel milk works, this link will take you to an earlier blog entry on camel milk.

If I were to consider all aspects involved with PANDAS, this is how I would approach it (wait, this is how I DID approach it, although in a slightly different order).
So yep, doctors are finally on board with PANDAS, but what exactly does that mean?  Do you also want their assistance with autism? I don't.

Be careful what you wish for.

UPDATE December 8th...This just in  from MercuryExposure.org!

From a 1984 study by Rowland et al. Antibiotics and Milk play a role in the efficency of Hg Excretion. In this study rats were given high doses of oral antibiotics the half-life for excretion of mercury increased from 10 days to >100 days. If the rats were also on a milk diet the excretion half-life increased to over 300 days. These results are consistent with the theory that demethylation of methylmercury by intestinal microflora is a major factor determining the excretion rate of mercury.
Effects of Diet on Mercury Metabolism and Excretion in Mice Given Methylmercury: Role of Gut Flora

ABSTRACT.
Mice fed either (1) a pelleted rodent diet, (2) evaporated milk, or (3) a synthetic diet (high protein, low fat) exhibited different rates of whole body mercury elimination and fecal mercury excretion after exposure (per os) to methylmercuric chloride. The percentage of the total mercury body burden present as mercuric mercury was highest (35.3%) in mice fed the synthetic diet (which had the highest rate of mercury elimination) and lowest (6.6%) in the animals having the lowest mercury elimination rate (milk-fed mice). Mice fed the syn-thetic diet had lower mercury concentrations and had a higher proportion of mercuric mer-cury in their tissues than the mice from the other dietary groups. Treatment of the mice with antibiotics throughout the experimental period to suppress the gut flora reduced fecal mer-cury excretion and the dietary differences in whole body retention of mercury. Tissue mercury concentrations and proportion of organic mercury in feces, cecal contents, liver, and kidneys were increased by antibiotic treatment of mice fed the pelleted or synthetic diets.
These results are consistent with the theory that demethylation of methylmercury by intestinal microflora is a major factor determining the excretion rate of mercury.

Discussion
The marked diet-related differences in whole body retention of Hg after MeHg exposure confirm the re-sults of Landry et al. 3 In addition, the differences in whole body retention were reflected in the amount or concentration of Hg present in the carcass (the major site of deposition of Hg in the mice), brain, blood, liver, and kidneys. The effect of diet on Hg concentration in brain (a target organ for MeHg toxicity) suggests that diet may influence MeHg-induced neurotoxicity since the concentration of Hg in tissues, particularly the central nervous system, has been correlated with the inci-dence of neurotoxicity in rats and mice.· 19 20

The three diets used in this study have many differences which make it difficult to differentiate the effects of specific dietary components1 although it would appear that dietary fiber is not an important factor governing the rate of Hg excretion since both the milk and GIBCO diets contained little indigestible residues.

Although differences in concentrations of Se were found in the three diets, it is unlikely that these were responsible for the differences in Hg elimination rates since the RMH3000 diet contained by far the highest Se concentration, yet mice fed this diet had an intermediate rate of Hg elimination. These results agree with those of Stil-lings el al., 21 who found that though dietary Se reduced the toxicity of MeHg, it did not appear to influence Hg elimination in feces or urine.

Over short time periods (up to 5 hrl co-administration of MeHgCI and low-molecular-weight thiol compounds has been shown to decrease blood Hg concentration and increase Hg accumulation by various organs by comparison to MeHgCI given alone. 22-24

Thus, differences in thiol concentrations in the diets and tissues may be responsible for diet-related changes in HHg tissue concentrations. However, in the present study, the thiol concentrations of the three diets were similar, and although some differences were detected in concentration of nonprotein-bound thiols in liver, they could not be correlated with Hg excretion rates or tissue Hg levels since mice fed milk or GIBCO diets had almost identical hepatic thiol concentrations. The con-centration of sulfhydryl compounds in the small intes-tine was highest in those mice fed milk probably due to an increase in glutathione from bile, because the ma-jority of the sulfhydryl groups were not protein-bound. However, it seems unlikely that differences in intestinal thiol concentration significantly affect Hg excretion rate since the sulfhydryl concentrations were greatly in excess of the Hg concentration to which the mice were exposed. It is noteworthy that the administration of MeHgCI increased (by 1-2 JLmoles/g tissue) the concentration of nonprotein-bound thiols in the livers of mice in all dietary groups, presumably affecting an increased synthesis of glutathione in bile.
It is possible that diet may also affect the whole body elimination of Hg via an effect on excretion of Hg in bile, since age-related changes in Hg elimination, can be as-cribed, at least in part, to changes in biliary excretion. 25

The differences in the amount of mercuric Hg in the whole body (Table 2), in the various tissues (Tables 3 and 4), and in cecal and colon contents (Fig. 4) in the animals fed the different diets suggest that diet-induced differences in Hg elimination are related to the extent of MeHg demethylation by the animals. The mice with the highest rates of Hg elimination, namely those fed GIBCO diet, had the highest proportion of their Hg body burden as mercuric Hg.

The previously demonstrated ability of the intestinal microilora to demethylate MeHg6 and its capacity to alter its metabolic activity in response to dietary modifi-cation 13•16 suggest that diet-induced changes in demeth-ylating activity of the gut flora are responsible for the differences in Hg elimination seen. Tlw results of the present study lend support to this theory.

It is clear that in all dietary groups a large proportion of total Hg in the gut was present in the mercuric form, especially in the cecum and colon. In particular, the GIBCO-fed animals reatained very high levels of Hg in the cecum and colon. Furthermore, the major route of excretion of Hg was the feces with only small amounts emerging in the urine, and in the GIBCO-fed mice the increased Hg elimination occurred via the feces rather than the urine. This indicates that MeHg demethylation occurs at sites where the product, mercuric Hg, does not re-enter the general circulation since parenterally administered HgCI2 is excreted mainly in the urine (Landry et al., unpublished observation, 1982).

Treatment of the mice with antibiotics to sterilize the gut contents virtually eliminated the diet-related dif-ferences in whole body Hg retention, in Hg excretion in feces and urine, and in the amount of mercuric Hg in whole body, gut contents, and tissues (especially in liver and kidney). These results are consistent with the theory that demethylation by the gut flora is a major determinant of the rate of Hg excretion after MeHg ex-posure. The almost complete retention of the dose of MeHg (apparent elimination of half-times> 100 days) in the animals without a gut flora and the increase in MeHg concentration in blood and liver is also consis-tent with the theory since it would be expected that the greater proportion of MeHg relative to total Hg in the gut of antibiotic-treated animals would result in greater absorption of the administered mercury dose.

Landry et al. (unpublished observation), using mice give MeHgCI intramuscularly, have reproduced the dietary-related differences in Hg elimination seen in orally dosed animals, but the three diets had little effect on Hg retention after parenteral administration of HgCI,. It would appear, therefore, that if MeHg is demethylated, diet is unlikely to exert any differential effects on Hg ... retention, suggesting that the differential effects of diet oc-cur on demethylation or on excretion of MeHg in bile.
In the mice given antibiotics, some residual formation November/December 1984 [Vol. 39, (No.6)] of mercuric Hg was apparent (Table 2) suggesting that sites of demethylation other than the gut flora exist. One possible site is the liver, although enzymatic demethyla-tion of MeHg by this organ has been little studied. It is also possible that the slow release of inorganic Hg from MeHg in the presence of thiol compounds17 contributes to inorganic Hg formation in vivo. \1\€ have confirmed (unpublished observations, 1981) that this can occur in the presence of thiol concentrations found in bile and in the liver (approximately 5 ~-tmole/mll.

In conclusion, the results of this study confirm previous reports 10 that the gut flora is the major site of de-methylation of MeHg in the mouse and strongly suggest that dietary effects on Hg elimination rates are mediated by changes in demethylating activity of the flora. The result of a high demethylation rate would be the formation in the gut lumen of mercuric Hg which, being poorly absorbed, interrupts the enterohepatic recycling of MeHg. 4

Large variations have been reported in rates of elimi-nation of Hg in human populations exposed to MeHg.18 It is conceivable that this variation may be related to the wide variation in composition of gut flora among individuals.29 Furthermore, if the major differences in gut flora that have been observed in populations in different geographic areas 10 are reflected in their MeHg demethylation rates, it is possible that there are inter-individual as well as inter-regional differences in suscep-tibility to MeHg poisoning.

Effects of Diet on Mercury Metabolism and Excretion in Mice Given Methylmercury: Role of Gut Flora
I. R. ROWLAND, Ph.D. The British Industrial Biological Research Association Woodmansterne Road Carshalton, Surrvey, United Kingdom R. D. ROBINSON, M.S. R. A. DOHERTY, M.D. Department of Pediatrics Environmental Health Sciences Center University of Rochester Rochester, New York 14642
Archives of Environmental Health: An International Journal
Arch Environ Health
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